abstract：:We studied transcriptional activity in the higher avian center visual system (Wulst area) in acoustically guided defensive behavior in visually deprived and non-deprived nestlings to evaluate the effects of visual afferentation on functional involvement of visual structures in acoustically guided defensive behavior. E...

journal_title：Bulletin of experimental biology and medicine

authors： Korneeva EV,Tiunova AA,Alexandrov LI

更新日期：2012-09-01 00:00:00

abstract：:The cytotoxic effects of human blood serum were studied under normal and pathological conditions. The contribution of the complement system to the realization of this effect was demonstrated. Significant differences in the serum capacity to kill foreign cells were detected for healthy subjects and asthmatics. Bovine s...

journal_title：Bulletin of experimental biology and medicine

authors： Arkhipova EN,Cherepov AB,Medvedeva YS,Alchinova IB,Karganov MY

更新日期：2012-09-01 00:00:00

abstract：:We studied the effects of neurotensin dipeptide analog Dilept (N-caproyl-L-prolyl-L-tyrosine methyl ester) on dopamine metabolism and synthesis in the nucleus accumbens of Wistar rats. Dilept increased the levels of dopamine and its metabolites (homovanillic acid and dioxyphenylalanine) and stimulated dopamine turnove...

journal_title：Bulletin of experimental biology and medicine

authors： Shubenina EV,Kudrin VS,Klodt PM,Narkevich VB,Kuznetsova EA,Gudasheva TA,Ostrovskaya RU

更新日期：2012-09-01 00:00:00

abstract：:The level of antipaternal antileukocytic antibodies detected by flow cytometry is a parameter reflecting the efficiency of alloimmunization of women with reproductive disorders during preparation to pregnancy. The results of evaluation of antipaternal antileukocytic antibodies by two modifications of the method are pr...

journal_title：Bulletin of experimental biology and medicine

authors： Krechetova LV,Nikolaeva MA,Van'ko LV,Ziganshina MM,Golubeva EL,Stepanova EO,Sukhikh GT

更新日期：2012-09-01 00:00:00

abstract：:The effects of Ro 25-6981 (selective NMDA receptor blocker) in a dose stimulating neurogenesis on repeated learning, reversal learning, and memory reconsolidation were studied in adult rats in Morris water maze. Ro 25-6981 facilitated repeated learning 13 days after injection, but did not influence reversal learning. ...

journal_title：Bulletin of experimental biology and medicine

authors： Soloviova OA,Proshin AT,Storozheva ZI,Sherstnev VV

更新日期：2012-09-01 00:00:00

abstract：:We studied the impact of acute glycerol-induced renal failure on blood levels and daily urinary excretion of arginine, monomethylarginine, and asymmetric and symmetric dimethylarginine. Acute renal failure was accompanied by enhanced daily excretion of asymmetric and symmetric dimethylarginine, increased plasma level ...

journal_title：Bulletin of experimental biology and medicine

authors： Sukhovershin RA,Gilinsky MA

更新日期：2012-08-01 00:00:00

abstract：:The levels of himantane and its metabolites in daily urine and feces of rats were measured after intraperitoneal and oral dose of 25 mg/kg. The injected dose of the initial substance and 1.3% its metabolites were eliminated with excrements within 24 h after administration via both routes 0.23%. ...

journal_title：Bulletin of experimental biology and medicine

authors： Litvin EA,Bastrygin DV,Kolyvanov GB,Alekseyev KV,Zherdev VP

更新日期：2012-08-01 00:00:00

abstract：:Rat liver was examined by transmission electron microscopy after a single intravenous injection of nanosized magnetite suspension (0.1 g (Fe(3)O(4))/kg body weight). Magnetite particles were found in Kupffer's cells and hepatocytes. Accumulation of the particles by these two cell types was different. Morphometry of ma...

journal_title：Bulletin of experimental biology and medicine

authors： Mil'to IV,Sukhodolo IV,Miller AA

更新日期：2012-08-01 00:00:00

abstract：:Tetrapeptide H-Ala-Glu-Asp-Arg-OH enhances the expression of cytoskeletal (actin, tubulin, vimentin) and nuclear matrix proteins (lamin A, lamin C) in cultured mouse embryonic fibroblasts by 2-5 and 2-3 times, respectively. Thus, the previously reported cardioprotective activity of this tetrapeptide is determined by i...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Lin'kova NS,Polyakova VO,Kvetnoy IM,Benberin VV,D'yakonov MM,Titkov YS

更新日期：2012-08-01 00:00:00

abstract：:We studied cardiac pumping function in the offspring of rats subjected to swimming exercise and the offspring of untrained rats. The rat pups were adapted for swimming with stepwise increasing load from day 21 to 70 life. At the age of 21 and 70 days, offspring of trained rats showed lower HR and significantly higher ...

journal_title：Bulletin of experimental biology and medicine

authors： Valeev AM,Abzalov NI,Abzalov RA,Nigmatullina RR,Abzalov RR,Nikitin AS

更新日期：2012-07-01 00:00:00

abstract：:Adhesion activity of L. acidophilus NK1, L. fermentum 90 TS4, and C. albicans 506 B on female vaginal epithelium was studied. Adhesion of various lactobacillus species was hormone-dependent. Adhesion of C. albicans 506 B was not associated with estrogen level. The effects of synthetic drugs and phytopreparations used ...

journal_title：Bulletin of experimental biology and medicine

authors： Rybas YA,Bustamante RA,Kravtsov EG,Tchernitchin AN,Dalin MV

更新日期：2012-07-01 00:00:00

abstract：:Structure of arteries of different diameter in early and late periods of hypertension caused by experimental coarctation of the aorta was studied by histological and morphometric methods. Blood pressure was measured directly via catheterization of the common carotid artery and used for evaluation of hemodynamic in the...

journal_title：Bulletin of experimental biology and medicine

authors： Gansburgsky AN,Jaltsev AV

更新日期：2012-07-01 00:00:00

abstract：:Castration had no effect on baseline BP and vascular sensitivity to acetylcholine and deficiency of nitric oxide and prostacyclin in normotensive specimens. Castration of hypertensive specimens decreased BP and potentiated the hypotensive effects of acetylcholine, but did not modulate vascular sensitivity to the block...

journal_title：Bulletin of experimental biology and medicine

authors： Semyachkina-Glushkovskaya OV,Anishchenko TG,Kuznetsova AS,Kuznetsova YV,Bibikova OA,Sjestnova AA

更新日期：2012-06-01 00:00:00

abstract：:C57Bl/6 mice were intranasally infected with influenza virus A/H5N1 A/goose/Krasnoozerskoye/627/05. The mortality rate of animals reached 70% on day 14 of the disease. The lungs of animals were characterized by necroses, destruction of vessels, hemorrhagic and thrombotic complications, edematous syndrome, and early fi...

journal_title：Bulletin of experimental biology and medicine

authors： Kovner AV,Anikina AG,Potapova OV,Sharkova TV,Cherdanceva LA,Shkurupy VA,Shestopalov AM

更新日期：2012-06-01 00:00:00

abstract：:We studied ultrastructural reorganization of the colon transplant in delayed period after esophagoplasty. It was found that during functioning of the artificial esophagus, a complex of adaptive and pathologic processes occurs in the mucosa. Focal sclerosis of the mucosa and slight epithelial degeneration with hyperpla...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lapii GA,Chikinev YV,Sudovykh IE,Tokmakov IA

更新日期：2012-06-01 00:00:00

abstract：:We proposed new method for measuring dynamic changes in hunger motivation in rabbits in the course of satisfaction of nutritional need by weight, time, and rate parameters of effective food-procuring behavior. Transformation of the amount of food eaten into the electric signals was performed using electronic weighing ...

journal_title：Bulletin of experimental biology and medicine

authors： Dvoenko EE,Kromin AA,Maslov AN

更新日期：2012-05-01 00:00:00

abstract：:Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary oral administration of glycine almost completely prevented th...

journal_title：Bulletin of experimental biology and medicine

authors： Selin AA,Lobysheva NV,Vorontsova ON,Tonshin AA,Yaguzhinsky LS,Nartsissov YR

更新日期：2012-05-01 00:00:00

abstract：:Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...

journal_title：Bulletin of experimental biology and medicine

authors： Yavisheva TM,Shcherbakov SD

更新日期：2012-05-01 00:00:00

abstract：:Administration of granulocyte CSF preparation to patients with chronic heart failure produced a hemostimulating effect and increased the content of leukocytes and neutrophils in the peripheral blood. Granulocyte CSF induced mobilization of bone marrow progenitor cells into the peripheral blood. The content of hemopoie...

journal_title：Bulletin of experimental biology and medicine

authors： Konenkov VI,Pokushalov EA,Poveshchenko OV,Kim II,Romanov AB,Guleva NA,Bernvald VV,Soloviova AO,Yankayte EV,Poveshchenko AF,Karaskov AM

更新日期：2012-05-01 00:00:00

abstract：:We studied reflection of artificially induced and amplified food motivation in impulse activity of the masticatory muscles during electrostimulation of "hunger center" of the lateral hypothalamus in the absence and presence of food. The threshold stimulation of the lateral hypothalamus in hungry and satiated animals i...

journal_title：Bulletin of experimental biology and medicine

authors： Ignatova JP,Kromin AA

更新日期：2012-04-01 00:00:00

abstract：:cDNA encoding VEGF and Ig-like extracellular domains 2-4 of VEGFR-1 (sFlt-1(2-4)) were cloned into prokaryotic expression vectors pET32a and pQE60. Recombinant proteins were purified (metal affinity chromatography) and renatured. Chemiluminescent study for the interaction of recombinant VEGF and sFlt-1(2-4) showed tha...

journal_title：Bulletin of experimental biology and medicine

authors： Leopol'd AV,Baklaushev VP,Korchagina AA,Shein SA,Grinenko NF,Pavlov KA,Ryabukhin IA,Chekhonin VP

更新日期：2012-04-01 00:00:00

abstract：:We studied high-resolution (1)H nuclear magnetic resonance spectra of the serum and serum albumin from patients with the first episode of schizophrenia and healthy individuals. A relative increase in signal intensities of CH(2) protons in serum LDL and VLDL in schizophrenia was demonstrated. Higher intensities of CH(2...

journal_title：Bulletin of experimental biology and medicine

authors： Babushkina TA,Klimova TP,Peregudov AS,Gryzunov YA,Smolina NV,Dobretsov GE,Uzbekov MG

更新日期：2012-04-01 00:00:00

abstract：:The effect of a 40-day toluene inhalation on learning of young and adult rats was examined in a multi-branched maze. Experimental rats of both age groups needed more time to pass the maze and made more errors than controls. This impairment was observed in young rats immediately after termination of toluene inhalation ...

journal_title：Bulletin of experimental biology and medicine

authors： Bikashvili TZ,Chilachava LR,Gelazonia LK,Japaridze NJ,Zhvania MG,Lordkipanidze TG,Okuneva VG

更新日期：2012-03-01 00:00:00

abstract：:The effects of fullerene C(60) nanocomposites on human platelet aggregation induced by ADP, ristocetin, and collagen were studied. The nanocomposite containing fullerene C(60) in polyvinyl pyrrolidone solution did not change platelet aggregation, while fullerene C(60) in crown ether and Twin-80 solutions inhibited ADP...

journal_title：Bulletin of experimental biology and medicine

authors： Vaschenko VI,Samonin VV,Popov VA,Antonenkova EV,Nikonova VJ,Vilyaninov VN,Podvjaznikov ML,Kidalov VN,Titulova TB,Vaschenko TN

更新日期：2012-03-01 00:00:00

abstract：:The effects of neural progenitor and hemopoietic stem cells on C6 glioma cells were studied in in vivo and in vitro experiments. Considerable inhibition of proliferation during co-culturing of glioma cells with neural progenitor cells was revealed by quantitative MTT test and bromodeoxyuridine incorporation test. Labe...

journal_title：Bulletin of experimental biology and medicine

authors： Baklaushev VP,Grinenko NF,Savchenko EA,Bykovskaya SN,Yusubalieva GM,Viktorov IV,Bryukhovetskii AS,Bryukhovetskii IS,Chekhonin VP

更新日期：2012-02-01 00:00:00

abstract：:An important role in the development of the immune response is played by macrophages that acquire either anti-inflammatory M1 or anti-inflammatory M2 phenotype depending on their microenvironment. The possibility of targeted reprogramming of the initial M2 macrophage phenotype towards M1 phenotype and vice versa using...

journal_title：Bulletin of experimental biology and medicine

authors： Lyamina SV,Kruglov SV,Vedenikin TY,Borodovitsyna OA,Suvorova IA,Shimshelashvili ShL,Malyshev IY

更新日期：2012-02-01 00:00:00

abstract：:During left-ventricular myocardial ischemia, the decrease in the venous return is determined by reduction of cardiac output, which results from heart rate deceleration and decrease in left-ventricular stroke volume. The latter is related to a decrease in myocardial contractility and blood storage in the pulmonary circ...

journal_title：Bulletin of experimental biology and medicine

authors： Evlakhov VI,Poyassov IZ

更新日期：2012-02-01 00:00:00

abstract：:Electron microscopic study of changes in cultured cells caused by Vibrio cholerae recombinant hemagglutinin/protease (HA/P) showed significant structural changes, most pronounced in HeLa and L-929 cells not forming a compact monolayer with tight junctions between the cells: formation of numerous vesicles on the cell s...

journal_title：Bulletin of experimental biology and medicine

authors： Sayamov SR,Monakhova EV,Fedorenko GM,Tkacheva TI,Markina OV,Alekseeva LP,Pisanov RV,Bardakhchian EA

更新日期：2012-02-01 00:00:00

abstract：:We studied the effect of simvastatin (24 mg/kg per os for 30 days) on DNA synthesis ((3)H-thymidine autoradiography) and free radical oxidation (chemiluminescent method) in the gastric mucosa of albino mice under normal conditions and in ulcerative process induced by single indometacin administration. Simvastatin trea...

journal_title：Bulletin of experimental biology and medicine

authors： Timoshin SS,Bragina VV,Lebedko OA,Sazonova EN,Zhivotova EY,Fleischman MY

更新日期：2012-01-01 00:00:00

abstract：:We studied the mechanisms of induction of recombinase activity in peripheral T cells of patients with autoimmune type 1 diabetes mellitus. It was shown that the presence of CD40 on T cell membrane (not typical of these cells) is crucial for this process: expression of recombinase RAG-1 in diabetic patients was detecte...

journal_title：Bulletin of experimental biology and medicine

authors： Kuklina EM,Gorbunova OL,Smirnova EN

更新日期：2012-01-01 00:00:00

abstract：:Here we present the results of histochemical detection of 3β-hydroxysteroid dehydrogenase in neurons of the neocortex, cerebellum, and brainstem. The positive reaction was observed in a low number of neocortical, midbrain, and pontine neurons. The maximum number of positive neurons was detected in the cerebellar corte...

journal_title：Bulletin of experimental biology and medicine

authors： Ryzhavskii BY,Litvintseva VM

更新日期：2012-01-01 00:00:00

abstract：:The relationships between open field behavior, initial nociceptive thresholds, and immunoreactivity assessed according to the development of hyperthermia triggered by LPS pyrogenal were examined in Wistar rats. Behaviorally active animals demonstrated higher nociceptive thresholds and greater immunoreactivity in compa...

journal_title：Bulletin of experimental biology and medicine

authors： Abramova AY,Abramov YB

更新日期：2011-12-01 00:00:00

abstract：:We studied the role of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) in functional differentiation of HC11 mouse mammary gland cells. It was found that both IGF-1 and IGF-2 activate the expression of milk protein β-casein in the presence of prolactin and hydrocortisone. It was found that β-casein expression is...

journal_title：Bulletin of experimental biology and medicine

authors： Shushanov SS

更新日期：2011-12-01 00:00:00

abstract：:The content of MMP-8 and MMP-9 in oral fluid of 145 patients (95 women and 50 men, 18-52 years) was measured by enzyme immunoassay. We examined 63 subjects with the intact periodontium and 82 patients with chronic generalized periodontitis (25 patients with mild disease, 45 patients with moderate disease, and 12 patie...

journal_title：Bulletin of experimental biology and medicine

authors： Kushlinskii NE,Solovykh EA,Karaoglanova TB,Bayar U,Gershtein ES,Troshin AA,Kostyleva OI,Grinin VM,Maksimovskaya LN,Yanushevitch OO

更新日期：2011-12-01 00:00:00

abstract：:We studied the interaction of the oculomotor, cervical, and vestibular systems using a specially developed technique. A series of two tests were performed on 26 healthy subjects and 42 patients with stages I-II Parkinson's disease receiving and not receiving treatment. In coordinated tests, all amplitude-time characte...

journal_title：Bulletin of experimental biology and medicine

authors： Shvetsov AY,Ivanova EA,Chigalejchik LA,Baziyan BKh

更新日期：2011-11-01 00:00:00

abstract：:The effects of ladasten and reference product imipramine (10 mg/kg) on the content of cytokines TNF-α, IL-6, IL-10, IL-1α, IL-2, IL-4, IL-5, IL-17, IFN-γ, and GM-CSF and behavior of male C57Bl/6 mice were studied on the model of a depression-like state induced by a single intraperitoneal injection of bacterial LPS in ...

journal_title：Bulletin of experimental biology and medicine

authors： Tallerova AV,Kovalenko LP,Durnev AD,Seredenin SB

更新日期：2011-11-01 00:00:00

abstract：:Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity...

journal_title：Bulletin of experimental biology and medicine

authors： Nasyrova RF,Sotnikova LS,Baystrukova NV,Krivoschchekova GV,Novitsky VV,Kupriyanova IE,Semke VY,Naslednikova IO,Baykov AN

更新日期：2011-11-01 00:00:00

abstract：:We demonstrated the influence of short peptides on the expression of signaling molecules in organotypic culture of the pineal gland from 3-month-old rats. Peptides Ala-Glu-Asp-Gly and Lys-Glu-Asp stimulate the expression of proliferative protein Ki-67 in pineal gland culture. These peptides as well as Glu-Asp-Arg and ...

journal_title：Bulletin of experimental biology and medicine

authors： Khavinson VKh,Linkova NS,Chalisova NI,Dudkov AV,Koncevaya EA

更新日期：2011-11-01 00:00:00

abstract：:Macrophage activity was studied after treatment with hybrid molecules obtained by condensation of terpenic acid residues (betulinic and betulonic acids) and α-tocopherol analogues (α-tocopherol hemisuccinate and Trolox acid). As distinct from betulinic acid and α-tocopherol hemisuccinate, hybrid molecules did not exhi...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova AN,Belsky YP,Spivak AY,Danilets MG,Belska NV,Chalitova RR,Ligatcheva AA,Uchasova EG

更新日期：2011-10-01 00:00:00

abstract：:We studied etiologic structure of bacterial intestinal infections in monkeys of Adler nursery. A total of 533 monkeys with diarrhea syndrome and monkeys dead from intestinal infections, as well as clinically healthy monkeys and animals dead from other pathologies were examined by bacteriological and molecular-genetic ...

journal_title：Bulletin of experimental biology and medicine

authors： Ardasheliya SN,Kalashnikova VA,Dzhikidze EK

更新日期：2011-10-01 00:00:00